A Comparison of the Decline in Glomerular Filtration Rate between Elderly Patients with Diabetes and those without Diabetes in Southwest China-Reference-Cited by-同舟云学术

A Comparison of the Decline in Glomerular Filtration Rate between Elderly Patients with Diabetes and those without Diabetes in Southwest China

Published:2024-09 Issue:12 Volume:24 Page:1371-1376
ISSN:1871-5303
Container-title:Endocrine, Metabolic & Immune Disorders - Drug Targets
language:en
Short-container-title:EMIDDT

Author:

Yi Qing-Hua¹,Wang Hong-Liang¹,Hou Yun²,Xu Lang²,Tian Wei-Li²,Zhang Yi-Xuan³,Xu Yu-Shan⁴,Shi Jia-Bin⁵

Affiliation:

1. Department of Nephrology, Kunming Guandu District People’s Hospital, Kunming 650200, China;

2. Department of Internal Medicine, Community Health Service Center of Wujing Street, Guandu District, Kunming 650200, China

3. Department of Nephrology, Kunming Guandu District People’s Hospital, Kunming 650200, China

4. Department of Internal Secretion, First Affiliated Hospital of Kunming Medical University, Kunming 650200, China

5. Department of Logistics, Kunming Guandu District People’s Hospital, Kunming 650200, China

Abstract

Objective: To investigate the effect of high blood glucose on the decline in the estimated glomerular filtration rate (eGFR) in the elderly. Methods: We compared the decline in eGFR of diabetic and non-diabetic groups in the noninterventional state and analyzed the effect of hyperglycemia on the decline in eGFR among the elderly in a retrospective analysis of 1,223 cases of elderly people aged 65 years or older with a 4-year follow-up period. Results: The prevalence of diabetes in the elderly increased significantly from 12.67% in 2017 to 16.68% in 2021. The rate of decline in eGFR in patients with diabetes was higher than in the population without diabetes, at 9.29% and 5.32%, respectively (both p < 0.05). Conclusion: The results of this study revealed that the prevalence of diabetes in the elderly increased significantly, and there is a more rapid decrease in the eGFR levels in those with diabetes than those without diabetes.

Publisher

Bentham Science Publishers Ltd.