Diagnostic Role of Tomography in Addison's Disease due to Adrenal Tuberculosis: A Case Report

Author:

Quiroz-Aldave Juan Eduardo1ORCID,Durand-Vásquez María del Carmen1ORCID,Gamarra-Osorio Elman Rolando2ORCID,Zavaleta-Aldave Sara Elizabeth3ORCID,Zavaleta-Aldave Alejandra Noemí4ORCID,Rodríguez-Reyna Jorge5ORCID,Quesquén-García Cyntia Mileini6ORCID,Alberto Concepción-Urteaga Luis7,Pecho-Silva Samuel89ORCID,Rodríguez-Hidalgo Luis Alejandro7ORCID,Paz-Ibarra José1011ORCID,Concepción-Zavaleta Marcio José8ORCID

Affiliation:

1. Division of Non-communicable diseases, Endocrinology research line, Hospital de Apoyo Chepén, Chepén, Perú

2. Division of Endocrinology, Hospital Víctor Lazarte Echegaray, Trujillo, Perú

3. Division of Medicine, Centro de Salud Mental Comunitario 'Flor de Loto', San Ignacio, Perú

4. School of Medicine, Universidad Nacional de Cajamarca, Cajamarca, Perú

5. Tomonorte. Trujillo, Perú

6. Division of Public Health, Red de Salud Chepén, Chepén, Perú

7. Division of Pneumology, Hospital Regional Docente de Trujillo, Trujillo, Perú

8. Universidad Científica del Sur, Lima, Perú

9. Division of Pneumology, Hospital Nacional Edgardo Rebagliati Martins, Lima, Perú

10. Department of Medicine, School of Medicine, Universidad Nacional Mayor de San Marcos, Lima, Peru

11. Division of Endocrinology, Hospital Nacional Edgardo Rebagliati Martins, Lima, Perú

Abstract

Introduction:: Adrenal tuberculosis remains the main cause of primary adrenal insufficiency (PAI) in tuberculosis (TB)-prevalent regions. This case report details the presentation of PAI due to adrenal TB, where the etiological diagnosis involves Abdominal Computed Tomography (CT). Case Report: A 37-year-old Peruvian woman with a history of TB contact displayed symptoms of adrenal insufficiency. PAI diagnosis was established, and CT imaging unveiled bilateral adrenal enlargement with calcifications. Treatment with prednisone and anti-TB therapy led to symptomatic improvement. Unfortunately, she succumbed to pneumonia after ten months of follow-up. Discussion: Adrenal TB must be considered in endemic regions and in the presence of a TB history. CT serves as a valuable diagnostic tool, particularly in settings with limited resources, revealing adrenal enlargement and calcifications. Conclusion: In patients with PAI, epidemiological history of TB, and when a rapid biopsy is not feasible, CT proves to be a valuable diagnostic method.

Publisher

Bentham Science Publishers Ltd.

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