Neonatal Microbiome: Is it still Beneficial?

Author:

Shawky Elfarargy Mohamed12ORCID,hamdy Elbadry Dalia3,Roshdy Ahmad41,Elhady Hany56

Affiliation:

1. Department of Pediatrics, College of Medicine, Jouf University, KSA

2. Department of Pediatrics, Faculty of Medicine, Tanta University, Egypt

3. Department of Pediatrics, El Menshawy General Hospital, Tanta, Egypt

4. Department of Pediatrics, College of Medicine, Assiut University, Egypt

5. Department of Surgery, College of Medicine, Alazhar University, Egypt

6. Department of Surgery, College of Medicine, Jouf University, KSA

Abstract

abstract: The neonatal microbiome includes all the microorganisms living within or on the surface of the newborn, as well as their genes (i.e., bacteria, fungi, and viruses), which are composed mainly of bacteria. The majority of these microorganisms reside in the gastrointestinal tract (GIT), which is known as the gut microbiome. They include trillions of microbes, which exceed the total number of neonate cells. In this study, we have examined factors affecting neonatal microbiome colonization, various phyla of the microbiome in neonates, and their characteristics. In addition, we have discussed symbiosis and dysbiosis, precipitating diseases, breast milk’s role in the neonatal gut microbiome, prebiotics, probiotics, postbiotics, and synbiotics, as well as the airway or respiratory microbiome, and the main role of the neonatal microbiome. We have also discussed neonatal mycobiome and neonatal virome, as well as the research done on the neonatal microbiome.

Publisher

Bentham Science Publishers Ltd.

Subject

Immunology and Allergy,Endocrinology, Diabetes and Metabolism

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