Silicon Quantum Dots: Promising Theranostic Probes for the Future

Author:

Sivasankarapillai Vishnu Sankar1,Jose Jobin2,Shanavas Muhammad Salman3,Marathakam Akash4,Uddin Md. Sahab5,Mathew Bijo6

Affiliation:

1. Department of Chemistry, NSS Hindu College, Changanacherry, Kerala-686102, India

2. Department of Pharmaceutics, NGSM Institute of Pharmaceutical Science, NITTE Deemed to be University, Mangaluru-575018, India

3. Department of Chemistry, Sree Narayana College, Punalur, Kollam-691305, India

4. Department of Pharmaceutical Chemistry, National College of Pharmacy, Calicut 673602, Kerala, India

5. Department of Pharmacy, Southeast University, Dhaka, Bangladesh

6. Division of Drug Design and Medicinal Chemistry Research Lab, Department of Pharmaceutical Chemistry, Ahalia School of Pharmacy, Palakkad 678557, Kerala, India

Abstract

Nanotechnology has emerged as one of the leading research areas involving nanoscale manipulation of atoms and molecules. During the past decade, the growth of nanotechnology has been one of the most important developments that have taken place in the biomedical field. The new generation nanomaterials like Quantum dots are gaining much importance. Also, there is a growing interest in the development of nano-theranostics platforms in medical diagnostics, biomedical imaging, drug delivery, etc. Quantum dots are also known as nanoscale semiconductor crystals, with unique electronic and optical properties. Recently, silicon quantum dots are being studied extensively due to their less-toxic, inert nature and ease of surface modification. The silicon quantum dots (2-10nm) are comparatively stable, having optical properties of silicon nanocrystals. This review focuses on silicon quantum dots and their various biomedical applications like drug delivery regenerative medicine and tissue engineering. Also, the processes involved in their modification for various biomedical applications along with future aspects are discussed.

Publisher

Bentham Science Publishers Ltd.

Subject

Clinical Biochemistry,Drug Discovery,Pharmacology,Molecular Medicine

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