A Review on PCR and POC-PCR - A Boon in the Diagnosis of COVID-19

Author:

Amuthalakshmi Sivaperuman1ORCID,Sindhuja Singaravelan1ORCID,Nalini Calambur Nagarajan1ORCID

Affiliation:

1. Department of Pharmaceutical Analysis, C.L. BaidMetha College of Pharmacy, Chennai-600 097, Tamil Nadu, India

Abstract

Abstract: Ever since the global spread of covid 19, PCR predominantly took the lead in the diagnosis. It amplifies a particular DNA target sequence into millions of copies. To simplify the laboratory-dependent disease diagnosis, the point of care diagnostics (POC) paved the way for lab-on-a-chip-technology. Succeeding that, POC integrated with PCR stole the limelight. This review points out the various diagnostic methods of covid 19 based on PCR and POC-PCR along with its principles, and types clustered regularly interspaced short palindromic repeats (CRISPR) based assays for the rapid, accurate, and easier detection of covid 19.

Publisher

Bentham Science Publishers Ltd.

Subject

Pharmaceutical Science,Molecular Medicine,Biochemistry,Biophysics

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