Ionic Liquids, Microextraction Methods and Capillary Electrophoresis in Biomedical Research

Author:

Miękus Natalia1ORCID,Ceraficka Martyna1,Chyła Marta1,Durska Aleksandra1,Bączek Tomasz1ORCID

Affiliation:

1. Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Medical University of Gdansk, al. Gen. J. Hallera 107, 80-416 Gdansk, Poland

Abstract

The review aims to present the importance of implementing microextraction-, capillary electrophoresis- and ionic liquid-based approaches in biomedical research. These analytical strategies could improve the biochemical diagnosis of various life-threatening diseases, aid in the search for therapeutic agents, and discover drug targets. They could be used when designing newer, safer medicinal products. All the proposed analytical approaches meet the requirements of “green chemistry”- based methods, which is relevant nowadays in view of the pollution of the Earth becoming a severe problem. The review is divided into three main sections, and biomedical examples of the application of each presented approach are discussed. It is assumed that the undoubted advantages of ionic liquid-, microextraction- and capillary electrophoresis-based methods will speed up their use in the study of various clinically important analytes from different biological fluids and tissue samples.

Publisher

Bentham Science Publishers Ltd.

Subject

Pharmaceutical Science,Molecular Medicine,Biochemistry,Biophysics

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