Affiliation:
1. Department of Analytical Chemistry, Faculty of Pharmacy, Ankara University, Ankara, Turkey
Abstract
Introduction:Schizophrenia is seizures accompanied by severe psychotic symptoms, and a steady state of continuation in the form of periods of stagnation. Antipsychotics are now the basis of treatment for schizophrenia and there is no other molecule that is antipsychotic priority in treatment. Antipsychotics can be classified into two groups; dopamine receptor antagonists such as promazine, fluphenazine etc. and serotonin-dopamine antagonists including risperidone, olanzapine, ziprasidone, aripiprazole etc.Materials and Methods:Electrochemical methods have been used for the determination of antipsychotic agent just as used in the determination of many drug agents. Nearly all of the antipsychotics are electroactive and can be analyzed by electrochemical methods. Electroanalytical methods offer generally high sensitivity, are compatible with modern techniques, have low cost, low requirements, and compact design. Among the most commonly used types, there are cyclic voltammetry, differential pulse voltammetry, square wave voltammetry and linear sweep voltammetry.Conclusion:The aim of this review is to evaluate the main line and the advantages and uses of electroanalytical methods that employed for the determination of antipsychotic medication agents used in schizophrenia. Moreover, applications of the methods to pharmaceutical analysis of Antipsychotics upto- date is also summarized in a table.
Publisher
Bentham Science Publishers Ltd.
Subject
Pharmaceutical Science,Molecular Medicine,Biochemistry,Biophysics
Reference157 articles.
1. Sadock B.J.; Sadock, V.A.; Çeviri editörü Bozkurt A. Kaplan & Sadock Klinik Psikiyatri. 4.baskı İstanbul: Güneş Tıp Kitapevleri 2009.
2. Arinami T, Hamaguchi H, Itokawa M, Enguchi H, Tagaya H, Yano S, Shimizu H. Association of dopamine D receptor molecular variant with schizophrenia.
3. Kane JM, Correll CU. Pharmacologic treatment of schizophrenia.
4. Van Os J, Kapur S. Schizophrenia.
5. Hennekens CH, Hennekens AR, Hollar D, Casey DE. Schizophrenia and increased risks of cardiovascular disease.
Cited by
6 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献