Affiliation:
1. Department of Chemistry, S. S. Khanna Girls’ Degree College, Prayagraj 211001, Uttar Pradesh, India
Abstract
Abstract:
Biologically active compounds play a very important role in our daily life. Almost all the biologically active compounds contain heteroatoms and among these a major portion are heterocycles. Heterocycles are a significant component in drug development programs. Drugs containing a heterocyclic moiety are highly valued resources in the fight against human and animal diseases and disorders. Some of these compounds are utilized as anticonvulsants antivirals, anti-inflammatory, and central vasodilators, while others are used as nontherapeutic anthelmintics, diuretics, anti-hypertensives, uricosurics, fungicides, bactericides, herbicides. In this review, we have discussed the chemistry of heterocyclic compounds such as Quinoxaline, Triazole, Pyrimidine, Pyridine, Oxadiazole, Thiazole, Indole, and Azepine. Besides some of their recent synthetic methodologies, their pharmaceutical importance is also discussed. Undoubtedly, the contents of this review will motivate readers to do more novel work in this area which will accelerate the journey towards the exploration of the pharmacological activity of heterocyclic compounds.
Publisher
Bentham Science Publishers Ltd.
Cited by
16 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Design, synthesis, characterization, structure-activity relationship, and molecular docking studies of novel 2,3-dihydropyrimidin-4(5H)-one and pyrimido[5,4–c] pyridazine-4-carbonitrile derivatives with biological evaluation;Journal of Molecular Structure;2024-12
2. Investigating the antibacterial potential of novel N-Boc isatin Schiff bases: Combining synthesis with in-vitro and in-silico studies;Journal of Molecular Structure;2024-10
3. Glucose-Water Synergy: An Organocatalytic System Driven synthesis of
Benzimidazolo[2,3-b]quinazolinone and Benzothiazolo[2,3-b]quinazolinone
Derivatives;Current Organocatalysis;2024-09
4. Synthesis, crystal structure, antioxidant activity and molecular docking studies of 2-(1-(3-methyl-1-oxo-1,2,3,4-tetrahydronaphthalen-2-yl)ethyl)malononitrile;Journal of Molecular Structure;2024-09
5. Unveiling the promise of pyrimidine-modified CDK inhibitors in cancer treatment;Bioorganic Chemistry;2024-08