HSV-2 Induced Cerebellitis: A Case Report of HSV-2 Reactivation by SARS-CoV-2 Infection

Abstract

Background: Herpes simplex virus type 2 rarely causes encephalitis in humans. Some DNA viruses, such as HSV-1 and HSV-2, can be reactivated by COVID-19 infection. SARS-CoV-2 causes a wide spectrum of neurological deficits, such as stroke, delirium, movement disorders, and neuropathy. Case Presentation: An unusual manifestation of HSV-2 was diagnosed as cerebellitis in our patient. It was concluded that SARS-CoV-2 can reactivate DNA viruses, such as HSV-2. Here, we reported a 1-year-old female infant with cerebellitis due to herpes simplex virus type 2 infection. Conclusion: The patient was treated with intravenous acyclovir and oral prednisolone for three weeks. Finally, during her 9-month neurological follow-up, she was able to walk with minimal ataxia.