Partial Molar Pregnancy Coexisting with a Normal Diploid Fetus: A Case Report

Abstract

Introduction: A partial molar pregnancy is a variation of a molar pregnancy in which an embryo either develops incompletely or with multiple structural anomalies. The aim of this study was to present a rare case of partial molar pregnancy coexisting with a normal diploid fetus. Case presentation: A 32-year-old woman with gravid 3, Para 2 (2 previous cesarean sections) was referred to Ghaem hospital, an academic hospital of Mashhad University of Medical Sciences, Mashhad, Iran, in 2020 at 34 weeks of gestation due to labor pain. She had an ultrasound-based diagnosis of partial molar pregnancy with the normal female fetus at 30 weeks for the first time. Due to 2 previous cesarean sections and regular uterine contractions, she underwent a cesarean section at 34 weeks and 2 days. A normal female infant with a normal Apgar score was born. The postpartum period was complicated with preeclampsia. The pathological evaluation confirmed partial molar pregnancy. The neonatal Karyotype was 46 XX and the neonatal period was uneventful. Maternal serum β-hCG reached normal after 5 weeks of cesarean. Conclusion: Partial molar pregnancy with the coexisting normal fetus is a rare condition; however, it may complicate the pregnancy outcomes, which affect both mother and fetus. So early diagnosis and close follow-up may prevent catastrophic maternal and fetal complications.