Affiliation:
1. Department of Physiology, Faculty of Basic Medical Science, Kunming Medical University, Kunming, Yunnan, 650500,
China
2. Institute of Neuroscience, Kunming Medical University, Kunming, Yunnan, 650500, China
Abstract
Abstract:
Autism is a class of developmental disorders with extremely high rates of disability,
affecting patients throughout their lives. There is no cure to date clinically, and early
rehabilitation interventions can improve some of the behavioral problems of autistic patients, but
these are limited by age and often have minimal effects in older adults with autism. Early
diagnosis is also necessary while developing effective autism therapies. At present, the early
diagnosis of autism is dependent on the search for effective markers in an attempt to screen
differentially expressed proteins in autistic patients using high-throughput assays, such as
synaptic scaffolding proteins, microtubule-associated proteins, apolipoproteins, immunoglobulin
G complement factor-related proteins, etc. It would also be a big step forward for mechanistic
studies of autism if a valid biomarker for autism could be found.
Funder
Kunming Medical Joint Project-Key Project
Key Area Research and Development Program of Guangdong Province
Kunming Medical University 100 Young and Middle-Aged Academic and Technical Backbone Training Program
Applied Basic Research Programs of Science and Technology Commission Foundation of Yunnan Province
Yunnan Province Ten Thousand Talents Program Young Top Talent Special Project
Joint Special Fund Project of Yunnan Provincial Science and Technology Department and Kunming Medical University for Applied Basic Research
Sichuan Science and Technology Program
Publisher
Bentham Science Publishers Ltd.
Subject
Biochemistry,General Medicine,Structural Biology