Affiliation:
1. Enzyme Biotechnology Laboratory, Department of Biochemistry, University of Agriculture, Faisalabad-38040, Pakistan
Abstract
:
An imbalance in oxygen supply to cardiac tissues or formation of thrombus leads to
deleterious results like pulmonary embolism, coronary heart disease and acute cardiac failure. The
formation of thrombus requires clinical encounter with fibrinolytic agents including streptokinase,
urokinase or tissue plasminogen activator. Irrespective to urokinase and tissue plasminogen
activator, streptokinase is still a significant agent in treatment of cardiovascular diseases.
Streptokinase, being so economical, has an important value in treating cardiac diseases in
developing countries. This review paper will provide the maximum information to enlighten all the
pros and cons of streptokinase up till now. It has been concluded that recent advances in
structural/synthetic biology improved SK with enhanced half-life and least antigenicity. Such
enzyme preparations would be the best thrombolytic agents.
Publisher
Bentham Science Publishers Ltd.
Subject
Biochemistry,General Medicine,Structural Biology
Cited by
12 articles.
订阅此论文施引文献
订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献