Αnti-KLK5/KLK7 Antibody-based Strategies for the Treatment of Epidermal Diseases
Author:
Affiliation:
1. Laboratory of Pharmacology, School of Pharmacy, Aristotle University of Thessaloniki, Thessaloniki, 54124, Greece
Abstract
Publisher
Bentham Science Publishers Ltd.
Subject
Drug Discovery,Pharmacology
Reference28 articles.
1. Sotiropoulou G.; Zingkou E.; Pampalakis G.; Reconstructing the epidermal proteolytic cascades in health and disease. J Pathol 2022,257(4),545-560
2. Brännström K.; Öhman A.; von Pawel Rammingen U.; Olofsson A.; Brattsand M.; Characterization of SPINK9, a KLK5-specific inhibitor expressed in palmo-plantar epidermis. Biol Chem 2012,393(5),369-377
3. Briot A.; Deraison C.; Lacroix M.; Kallikrein 5 induces atopic dermatitis-like lesions through PAR2-mediated thymic stromal lymphopoietin expression in Netherton syndrome. J Exp Med 2009,206(5),1135-1147
4. Zhu Y.; Underwood J.; Macmillan D.; Persistent kallikrein 5 activation induces atopic dermatitis-like skin architecture independent of PAR2 activity. J Allergy Clin Immunol 2017,140(5),1310-1322.e5
5. Billi A.C.; Ludwig J.E.; Fritz Y.; KLK6 expression in skin induces PAR1-mediated psoriasiform dermatitis and inflammatory joint disease. J Clin Invest 2020,130(6),3151-3157
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