The Regulation of Selenoproteins in Diabetes: A New Way to Treat Diabetes-Reference-Cited by-同舟云学术

The Regulation of Selenoproteins in Diabetes: A New Way to Treat Diabetes

Published:2024-06 Issue:20 Volume:30 Page:1541-1547
ISSN:1381-6128
Container-title:Current Pharmaceutical Design
language:en
Short-container-title:CPD

Author:

Liang Jing¹²,He Yiwen¹³,Huang Chunxia⁴,Ji Fengjie⁵,Zhou Xihong¹²,Yin Yulong¹²

Affiliation:

1. Key Laboratory of Agro-ecological Processes in Subtropical Region, Institute of Subtropical Agriculture, The Chinese Academy of Sciences, Changsha 410125, China

2. College of Advanced Agricultural Sciences, University of Chinese Academy of Sciences, Beijing 100049, China

3. Hunan Provincial Key Laboratory of Animal Intestinal Function and Regulation, Hunan International Joint Laboratory of Animal Intestinal Ecology and Health, College of Life Sciences, Hunan Normal University, Changsha 410081, China

4. School of Stomatology, Changsha Medical University, Changsha 410219, China

5. Tropical Crops Genetic Resources Institute, Chinese Academy of Tropical Agricultural Sciences, Haikou 571101, China

Abstract

Abstract: Selenium is an essential micronutrient required for the synthesis and function of selenoproteins, most of which are enzymes involved in maintaining oxidative balance in the body. Diabetes is a group of metabolic disorders characterized by high blood glucose levels over a prolonged period of time. There are three main types of diabetes: type 1, type 2, and gestational diabetes. This review summarizes recent advances in the field of diabetes research with an emphasis on the roles of selenoproteins on metabolic disturbance in diabetes. We also discuss the interaction between selenoproteins and glucose and lipid metabolism to provide new insights into the prevention and treatment of diabetes.

Funder

China Agriculture Research System of MOF and MARA

National Key Research and Development Program of China

Publisher

Bentham Science Publishers Ltd.

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