Niosomes as a Promising Therapeutic Approach against Colorectal Cancer: A Focus on the Delivery of Chemotherapeutics and Natural Products

Author:

Mollazadeh Samaneh1,Al-Asady Abdulridha Mohammed234,Barjasteh Amirhosein5,Latifi Hanieh5,Avan Amir67,Khazaei Majid78,Ryzhikov Mikhail9,Hassanian Seyed Mahdi1011

Affiliation:

1. Natural Products and Medicinal Plants Research Center, North Khorasan University of Medical Sciences, Bojnurd, Iran

2. Department of Medical Sciences, Faculty of Nursing, Warith Al-Anbiyaa University, Kerbala, Iraq

3. Department of Medical Sciences, Faculty of Dentistry, University of Kerbala, Kerbala, Iraq

4. Department of Pharmacology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

5. Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

6. Department of Human Genetics, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

7. Metabolic Syndrome Research Center, Mashhad University of Medical Sciences, Mashhad, Iran

8. Department of Medical Physiology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

9. School of Medicine, Saint Louis University, St. Louis, MO 63103, USA

10. Metabolic Syndrome Research Center, Mashhad University of Medical Sciences, Mashhad, Iran

11. Department of Clinical Biochemistry, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran

Abstract

Abstract: Nanotechnology has emerged as an effective approach to cancer treatment, including Colorectal Cancer (CRC). While conventional treatments, such as chemotherapeutic agents, are used to manage CRC, their efficacy can be improved using drug delivery systems that enhance their bioavailability and reduce side effects. Niosomes, polymeric nanoparticles, have shown promise as biocompatible vehicles that can transport hydrophilic and lipophilic molecules. This can result in reduced drug dosage and increased efficacy. This review examines the use of niosomal formulations as a delivery platform for treating CRC and provides practical insights into their clinical applications.

Funder

Mashhad University of Medical Sciences

Publisher

Bentham Science Publishers Ltd.

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