Affiliation:
1. Department of Physical Sciences, Chemistry Division, College of Science, Jazan University, P.O.Box. 114, Jazan
45142, Kingdom of Saudi Arabia
Abstract
Abstract:
Novel hydrazones 4, 5, and oxime 6 were produced from the reaction of ketone 3 with hydrazine,
phenylhydrazine, and hydroxylamine HCl, respectively. One pot multicomponent reaction of
chalcones 7a-c, 3-(1H-indol-3-yl)-3-oxopropanenitrile 8, and ammonium acetate in MeOH at reflux
temperature gave 2-(1H-indol-3-yl)-nicotinonitrile derivatives 10-12. Additionally, a one-pot reaction
of chalcone 7a, malononitrile or ethyl cyanoacetate, and ammonium acetate in AcOH at reflux temperature
afforded 6-aminopyridine derivatives 13 and 14, respectively.
Publisher
Bentham Science Publishers Ltd.
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