Affiliation:
1. Institute of Pharmaceutical Research, GLA University, Mathura - 281406, Uttar Pradesh, India
2. G.V.M College of
Pharmacy, Sonipat, Haryana 131001, India
Abstract
Abstract::
1, 3, 4-oxadiazole and its derivatives have significant anti-inflammatory and antimicrobial
property. Their precise mechanism of action is not known but it is postulated that they act
by inhibiting the biosynthesis of certain prostaglandins. 1, 3, 4-oxadiazoles are a class of heterocyclic
compounds with wide variety of biological and pharmacological activities. They have been
reported to possess analgesic, antimicrobial, antipyretic and anti-inflammatory properties. These
compounds are also active against a number of other inflammatory conditions such as arthritis,
gout etc. A wide variety of these compounds have been synthesized and some of them are under
clinical trials. In this review article, anti-inflammatory and antimicrobial activity of the 1, 3, 4-
oxadiazole shall be discussed.
Publisher
Bentham Science Publishers Ltd.
Subject
Organic Chemistry,Biochemistry
Cited by
1 articles.
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