Antioxidant Activities and Phenolic Composition of <i>Sarcococca saligna</i> Leaves-Reference-Cited by-同舟云学术

Antioxidant Activities and Phenolic Composition of Sarcococca saligna Leaves

Published:2024-10 Issue:10 Volume:21 Page:876-882
ISSN:1570-1786
Container-title:Letters in Organic Chemistry
language:en
Short-container-title:LOC

Author:

Sabir Syed Mubashar¹,Shahida Shabnam¹,Zeb Alam²,Abbas Syed Rizwan³,Hameed Muhammad Usman¹,Shanableh Abdallah⁴,Khan Muhammad Imran⁴,Ghernaout Djamel⁵,Lajimi Ramzi Hadj⁶⁷,Elgharbi Sarra⁶,Besbes Malek⁸,Elboughdiri Noureddine⁵

Affiliation:

1. Department of Chemistry, University of Poonch, Rawalakot, Azad Kashmir, Pakistan

2. Department of Biochemistry, University of Malakand, Chakdara, Pakistan

3. Department of Biological Science, Karakoram International University, Hunza Campus, Gilgit, Pakistan

4. Research Institute of Sciences and Engineering (RISE), University of Sharjah, Sharjah 27272, United Arab Emirates

5. Department of Chemical Engineering, College of Engineering, University of Hail, PO Box 2440, Ha’il 81441, Saudi Arabia

6. Department of Chemistry, College of Science, University of Ha’il, PO Box 2440, Ha'il 81441, Saudi Arabia

7. Laboratory of Water, Membrane and Environmental Biotechnology, Centre of Research and Water Technologies, Technopark of Borj-Cedria, BP 273, 8020 Soliman, Tunisia

8. Department of Biology, College of Science, University of Ha’il, PO Box 2440, Ha'il 81441, Saudi Arabia

Abstract

Abstract: Sarcococca saligna (D. DON) Muel is a vital plant with several steroidal alkaloids and is effective against syphilis, liver diseases, gastrointestinal tract disease, infections, and inflammation. The present study aimed to investigate the in vitro antioxidant activities and phenolic profile of S. saligna. High-performance liquid chromatography (HPLC) analysis has shown the presence of twelve phenolics namely kaempferol-3-O-glucoside, proanthocyanidin B1, quercetin-3-malonylglucoside- 7-glucoside, kaempferol-3-O-sophorotioside, Isorhamnetin-3-O-glucoside-7-O-rhamnoside, kaempferolhexoside, 4-O-Caffeoyl-5-O-p-coumaroylquinic acid, 3,4-Di-O-caffeoyl-5-O-feruloylquinic acid, 3,4-Di-O-feruloyl-5-O-caffeoylquinic acid, flavogalloyl-HHDP-gluconic acid (lagerstannin B), 3,4-di-O-caffeoylquinic acid and kaempferol-3-(caffeoyldiglucoside)-7-glucoside. The hot water extract showed the highest anti-lipid peroxidative activities. The IC50 value for 2,2-diphenyl-1- picrylhydrazyl (DPPH) radical scavenging activity was 71.5 ± 2.1 μg/mL. The extract could chelate the iron and possess reducing activities on phosphomolybenum assay. It is concluded that extracts of S. saligna are rich in antioxidants and contain essential phytochemicals.

Funder

Scientific Research Deanship at the University of Ha'il - Saudi Arabia

Publisher

Bentham Science Publishers Ltd.

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