On Water Synthesis of 3-Aryl-5,7-dimethyl-1,2,4-triazolo[4,3-a]pyrimidines
using Iodobenzene Diacetate
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Published:2023-05
Issue:5
Volume:20
Page:401-406
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ISSN:1570-1786
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Container-title:Letters in Organic Chemistry
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language:en
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Short-container-title:LOC
Author:
Aneja Deepak Kumar1ORCID,
Soni Rinku1ORCID,
Sihag Monika1ORCID,
Rani Neha1ORCID,
Kinger Mayank1ORCID
Affiliation:
1. Department of Chemistry, Chaudhary Bansi Lal University, Bhiwani, 127021, Haryana, India
Abstract
Abstract:
A simple and green methodology has been developed for the synthesis of 3-aryl-5,7-
dimethyl-1,2,4-triazolo[4,3-a]pyrimidines in water. Oxidative cyclization of 4,6-dimethyl-2-
pyrimidinylhydrazones of different aldehydes was achieved in good to excellent yield using
iodobenzene diacetate at room temperature. High efficiency, easy work-up, short reaction time,
non-toxicity of solvent and ambient temperature are the advantages of this methodology.
Publisher
Bentham Science Publishers Ltd.
Subject
Organic Chemistry,Biochemistry
Cited by
1 articles.
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