Significance of Molecular Docking in Developing Potent Antimicrobial 1,3,4-Thiadiazole Derivatives

Abstract

Abstract: New drug development has been a convoluted, costly, tedious, and difficult job. Overall, enormous sums of money are required for a new drug development pipeline through traditional methods. The pharmaceutical industry faces challenges in diminishing the research cost and time period for new drug discovery. Artificial intelligence has contributed to the industry for quicker, less expensive, and more successful drug designs by giving new paradigms such as computer-aided drug discovery. Recently, the fast development of computational tools for drug discovery is exhibiting remarkable effects on drug design. This article delivers knowledge and success stories of artificial intelligence via Computer Aided Drug Design (CADD) in Medicinal Chemistry and considers the assistance of molecular docking in developing anti-microbial thiadiazole derivatives during the last decade.