Affiliation:
1. Department of Chemistry, Shivaji University, Kolhapur, Maharashtra 416004, India
Abstract
Abstract:
An environmentally benign, simple, rapid synthesis of 1,2,4-triazolidine-3-thiones at
room temperature is reported using amino acid-derived Brønsted acidic ionic liquid L-proline nitrate
[Pro+NO3
-] from aldehyde and thiosemicarbazide in an aqueous medium. A cost-effective and
energy-efficient catalyst with the reusability of up to five cycles without significant loss in the catalytic
activity makes this protocol superior. A faster reaction and easy work-up with excellent yields
are the added advantages of this protocol.
Publisher
Bentham Science Publishers Ltd.
Subject
Organic Chemistry,Biochemistry