Miscellaneous Passerini Reaction for α-Acyloxy Carboxamide: Synthesis and Process Optimization Study-Reference-Cited by-同舟云学术

Miscellaneous Passerini Reaction for α-Acyloxy Carboxamide: Synthesis and Process Optimization Study

Published:2021-01-25 Issue: Volume:18 Page:
ISSN:1570-1786
Container-title:Letters in Organic Chemistry
language:en
Short-container-title:LOC

Author:

Jivani Amita J.¹,Kapadiya Khushal M.²^ORCID,Khunt Ranjan C.¹

Affiliation:

1. Chemistry Research Laboratory, Department of Chemistry, Saurashtra University, Rajkot- 360 005, Gujarat, India

2. Bio-Research and Characterization Centre, School of Science, Department of Chemistry, RK University, Rajkot- 360 020, Gujarat, India

Abstract

: An accelerating effect of “Phase Transfer Catalyst” as additive was exposed for the Passerini three-component reactions and the influence on the reaction rate was studied concerning direct involvement of reactant molecules. The most flexible reaction for the rapid formation of diverse “α-acyloxycarboxamides” using passerini reaction involved multicomponent reactions using miscellaneous 2-(prop-2-ynyloxy)benzaldehyde with various aromatic acid and slightly non-polar fragment i.e. 2-isocyano-2,3,3-trimethylbutane and the representative molecule was characterized with resepct to DEPT135 NMR technique.

Publisher

Bentham Science Publishers Ltd.

Subject

Organic Chemistry,Biochemistry

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