Phosphomolybdic Acid (PMA)-catalyzed One-pot Synthesis of 2,3- Dihydroquinazolines-Reference-Cited by-同舟云学术

Phosphomolybdic Acid (PMA)-catalyzed One-pot Synthesis of 2,3- Dihydroquinazolines

Published:2019-06-18 Issue:8 Volume:16 Page:683-687
ISSN:1570-1786
Container-title:Letters in Organic Chemistry
language:en
Short-container-title:LOC

Author:

Chen Chuanhuan¹,Xuejiao A.¹,Li Xia¹,Huang Guoli¹,Liu Bo¹

Affiliation:

1. School of Chemistry and Chemical Engineering, Yunnan Normal University, Kunming 650500, China

Abstract

We have developed a new method for the synthesis of 2,3-dihydroquinazolin-4(1H)-ones in good to excellent yields via phosphomolybdic acid (PMA)-catalyzed cyclocondensation of 2- aminobenzamides with aldehydes or ketones in N,N-dimethylformamide (DMF) at room temperature. The present method proves to be efficient in terms of short reaction time, high yield, simple workup and easy purification.

Funder

Science Research Foundation Teacher Projects of Yunnan Education Department

National Natural Science Foundation of China

Publisher

Bentham Science Publishers Ltd.

Subject

Organic Chemistry,Biochemistry

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