Ag(I)-promoted Decarboxylative Annulation of α-Oxocarboxylic Acids with (E)-3-(2-aminophenyl)-1-Phenylprop-2-en-1-ones Toward 3,4- Functionalized Quinolines

Author:

Fan Xiaodong1,Wang Chang1,Cheng Jiang1

Affiliation:

1. School of Petrochemical Engineering, and Jiangsu Key Laboratory of Advanced Catalytic Materials & Technology, Changzhou University, Changzhou 213164, China

Abstract

An efficient Ag-promoted decarboxylative cyclization of α-oxocarboxylic acids with (E)-3- (2-aminophenyl)-1-phenylprop-2-en-1-ones has been developed to afford a series of functionalized quinolines in moderate to good yields. This method was compatible with a variety of functional groups and provided an attractive method toward phenyl(2-phenylquinolin-3-yl)methanones.

Funder

Jiangsu Key Laboratory of Advanced Catalytic Materials & Technology

Key University Science Research Project of Jiangsu Province

National Natural Science Foundation of China

Publisher

Bentham Science Publishers Ltd.

Subject

Organic Chemistry,Biochemistry

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