Affiliation:
1. Department of Chemistry, Chaudhary Bansi Lal University, Bhiwani-127021, Haryana, India
Abstract
Abstract:
An iodobenzene diacetate (IBD)-mediated simple and green method was determined for
the intramolecular oxidative cyclization of 3-aryl-2-pyridiylhydrazones of different aromatic
aldehydes in an aqueous medium at room temperature. This efficient strategy provides a route to
the synthesis of 3-aryl-1,2,4-triazolo[4,3-a]pyridines in water which eliminates the requirement to
use costly and unsafe volatile organic solvents. All reactions were carried out by just stirring the
reaction components in water at room temperature. This protocol provides a wide substrate scope
and good functional group tolerance.
Funder
Council of Scientific and Industrial Research (CSIR), India
Chaudhary Bansi Lal University, Bhiwani
Publisher
Bentham Science Publishers Ltd.
Subject
Organic Chemistry,Biochemistry
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