Affiliation:
1. Instituto de Investigación en Biociencias, Centro Universitario de Los Altos, Universidad de Guadalajara, Tepatitlán
de Morelos, Jalisco, México
2. Laboratorio de Microbiología de Alimentos, Centro Universitario de Los Altos, Universidad
de Guadalajara, Tepatitlán de Morelos, Jalisco, México
3. Departamento de Ciencias Biomédicas, Centro
de Investigación Multidisciplinaria en Salud, Centro Universitario de Tonalá, México
Abstract
Abstract:
Green’ methodologies have become the main route for producing selenium nanoparticles
(SeNPs), as they do not involve toxic substances that can increase the reactivity of the synthesized nanoparticles
and are practical and inexpensive. Extracts from plants, bacteria, fungi, yeasts, ascorbic
acid, and polysaccharides are used to produce these nanoparticles. Plant extracts contain phytochemicals
that act as reducing and stabilizing agents, while bacteria, fungi, and yeasts can synthesize SeNPs
from metabolites secreted during their development or via intracellular mechanisms. Ascorbic acid is
also an excellent agent for reducing precursor metal salts, and polysaccharides act as stabilizing agents
for the synthesized nanoparticles. The SeNPs synthesized by these routes have desirable characteristics
for clinical applications since they are safe, non-toxic, and stable, with high biocompatibility and
bioavailability. In addition, they have antimicrobial, anti-cancer, anti-diabetic, anti-mosquito, antioxidant,
and anti-inflammatory activities, as revealed by both in vitro and in vivo studies.
Publisher
Bentham Science Publishers Ltd.
Subject
Organic Chemistry,Biochemistry