Heterogeneous Copper-catalyst Anchored on Chitosan Schiff Basemodified Carbon Nanotubes for Click Reaction

Author:

Kwak Soo-Jung1,Kim Seung-Hoi1ORCID,Shin Ueon Sang23ORCID

Affiliation:

1. Department of Chemistry, Dankook University, Cheonan, 31116, Republic of Korea

2. Department of Nanobiomedical Science, BK21 FOUR NBM Global Research Center for Regenerative Medicine, Dankook University, Cheonan, 31116, Republic of Korea

3. Institute of Tissue Regeneration Engineering (ITREN), Dankook University, Cheonan, 31116, Republic of Korea

Abstract

Abstract: A newly designed heterogeneous copper catalytic platform immobilizing copper (II) salt on chitosan Schiff base-modified carbon nanotubes was developed (Cu@CS-Py@CNT). The structure of the catalyst platform was fully characterized by spectroscopic analyses. The catalytic activity of the Cu@CS-Py@CNT was investigated in a one-pot synthesis of 1,4-disubstituted 1,2,3-triazoles by the regioselective click reaction using various benzyl halides or their surrogates, terminal alkynes, and sodium azide in an aqueous environment without using any external Cu-reducing agents.

Publisher

Bentham Science Publishers Ltd.

Subject

Organic Chemistry,Biochemistry

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