Affiliation:
1. Department of Applied Chemistry, Amity School of Engineering & Technology, Amity University Madhya Pradesh,
Maharajpura Dang, Gwalior-474 005, India
Abstract
Abstract:
An important bioactive heterocycle having several uses in medicinal chemistry, synthetic
organic chemistry, material chemistry, and natural product is indole along with its analogues. Many
bioactive indole-based heterocycles have important antibacterial, anti-inflammatory, analgesic, antiviral,
antimalarial, chemotherapeutic, antifungal, and anti-TB effects, as well as antioxidant capabilities.
Several well-known medications, including tadalafil, rizatriptan, sumatriptan, and fluvastatin are indole-
based potential bioactive compounds. Based on the existing and latest evidence, researchers have
focused on developing indole-based compounds with novel biological and pharmacological properties
for decades. Owing to useful bioactivities, we have described many bioactive indoles and their synthetic
methods in this review article.
Publisher
Bentham Science Publishers Ltd.
Subject
Organic Chemistry,Biochemistry