Convenient Synthesis of 2,4-disubstituted Chromeno[4,3-b]Pyridine by Microwave-Assisted, One- Pot, Three-Component Protocol

Abstract

Herein, an efficient and scalable synthesis of 2,4-diaryl substituted chromene [43-b] pyridine derivatives, using a multicomponent reaction strategy by microwave irradiation of 4-amino 2-oxo- 2H-chromene, aromatic aldehydes, and substituted anilines is described. This synthetic strategy was found to be very useful as it follows environment benign protocol. Also it gives a good outcome in terms of yield and requires a shorter reaction time.