Microwave Irradiation: Synthesis and Characterization of Substituted Pyranoquinolines

Abstract

A new series of pyrano[2,3-b]quinolines were synthesized from 3-formylquinolin-2(1H)- ones via Knoevenagel condensation followed by cyclization reaction of ethyl cyanoacetate using DMSO as solvent. This methodology is a simple; clean, fast, efficient, eco-friendly method with less reaction time, an improvement in the yield and purity of the product. The structures of newly synthesized compounds were confirmed by IR, NMR, Mass and elemental analysis.