Affiliation:
1. Department of Chemistry, Faculty of Science, King Abdul Aziz University, P.O. Box.42805 Jeddah 21551, Saudi Arabia
Abstract
Novel phosphorus compounds bearing fluorine substituted 1,2,4-triazolo[3,2-c][1,2,4]triazine derivatives have been synthesized, starting from ring closure reactions of 3-hydrazino-4-(4`- fluorophenyl)-5-(prydin-4`-yl)-1,2,4-trizole (4) with 1,2-bioxygen compounds followed by the treatment with functional phosphorus compounds. The new systems obtained were evaluated as molluscicidal targets against some snails. Structures of these targets were elucidated upon their elemental and spectral data.
Publisher
Bentham Science Publishers Ltd.
Subject
Organic Chemistry,Biochemistry
Cited by
3 articles.
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1. Synthetic approaches to 1,2,4-triazolo[5,1-c][1,2,4]triazin-7-ones as basic heterocyclic structures of the antiviral drug Riamilovir (“Triazavirin®”) active against SARS-CoV-2 (COVID-19);Organic & Biomolecular Chemistry;2022
2. Synthesis and Chemistry of Phosphorus Compounds Substituted by 1,2,4-Triazine Moieties as Medicinal Probes;HETEROCYCLES;2021
3. Synthesis and pharmacological evaluation of new fluorine substituted pyrimido[1,2-b][1,2,4]triazines and [1,3,5]-triazino-[1,2-b][1,2,4]triazines derived as CDK2 potential inhibitors;European Journal of Chemistry;2020-09-30