Multi-component Preparation of Pyrazolo[3,4-d]thiazolo[3,2-a]pyrimidines Using Solvent-free and HSBM Techniques

Author:

Roudbaraki Seyyed Jalal1,Ziyaadini Morteza2,Ghashang Majid3

Affiliation:

1. Department of Chemistry, Lahijan Branch, Islamic Azad University, Lahijan, Iran

2. Department of Marine Chemistry, Faculty of Marine Science, Chabahar Maritime University, Chabahar, Iran

3. Department of Chemistry, Najafabad Branch, Islamic Azad University, P.O. Box: 517; Najafabad, Iran

Abstract

Simple and clean access to pyrazolo[3,4-d]thiazolo[3,2-a]pyrimidine derivatives using solvent- free and HSBM techniques through the multi-component reaction of 3-methyl-1-phenyl-1Hpyrazol- 5-amine, 1-aryl-2-thiocyanatoethan-1-one and aromatic aldehydes are reported. Using 2-hydroxyethan-1-aminium acetate as an ionic liquid, the product in high yields is obtained.

Publisher

Bentham Science Publishers Ltd.

Subject

Organic Chemistry,Biochemistry

Reference18 articles.

1. Zhu J.; Wang Q.; Wang M.; Multicomponent Reactions in Organic Synthesis 2015

2. Abbasi-Dehnavi H.; Ghashang M.; Heterocycl Commun 2018,24,19-22

3. Ghashang M.; Res Chem Intermed 2016,42,4191-4205

4. Ghashang M.; Mansoor S.S.; Solaree L.S.; Sharifian-esfahani A.; Iran. J Catal 2016,6,237-243

5. Baziar A.; Ghashang M.; React Kinet Mech Catal 2016,118,463-479

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