Microwave Assisted Solvent Free One Pot Synthesis of N-acetyl-bis-indoles-Reference-Cited by-同舟云学术

Microwave Assisted Solvent Free One Pot Synthesis of N-acetyl-bis-indoles

Published:2019-05-30 Issue:7 Volume:16 Page:531-534
ISSN:1570-1786
Container-title:Letters in Organic Chemistry
language:en
Short-container-title:LOC

Author:

Ganesh K. Ravi¹,Murthy V. Narayana¹,Rao K. Raghavendra¹,Rao M.V. Basaveswara²,Murthy C.³,Raghunadh A.¹

Affiliation:

1. Technology Development Centre, Custom Pharmaceutical Services, Dr. Reddy’s Laboratories Ltd, Miyapur, Hyderabad 500049, India

2. Department of Chemistry, Krishna University, Machilipatnam 521001, Andhra Pradesh, India

3. Division of Chemistry, Department of Sciences and Humanities, Vignan's Foundation for Science, Technology and Research (Deemed to be University), Vadlamudi, Guntur 522 213, Andhra Pradesh, India

Abstract

The synthesis of various N-acetyl-bis-indole compounds has been achieved by one pot reaction of indole and acid chloride in the presence of silica sulfuric acid as a catalyst under microwave irradiation to moderate yields. The reaction has also been studied with different acid chlorides and solvents.

Publisher

Bentham Science Publishers Ltd.

Subject

Organic Chemistry,Biochemistry

Reference7 articles.

1. (a)Sundberg, R.J. Reactivity of 3-Cyanoacetylindole Derivatives: Synthesis of 3-Hydrazonopyrazolyl and 3-Thiadiazolyl Indole Derivatives, The Chemistry of Indoles, Academic Press New York. 1996. (b)Penieres-Carrill, G.; Garcia-Estrada, J.G.; Gutierrez-Ramirez, J.L. lvarez-Toledano, C. Green Chem., 2003, 5, 337.

2. Ji S-J, Wang S-Y, Zhang Y, Loh T-P.

3. Bourgeois P, Mesdouze J, Philogene E. Heterocycl.

4. Quartarone G, Charmet AP, Ronchin L, Tortato C, Vavasori A.

5. Jaganmohan C, Kumar KPV, Reddy GS, Mohanty S, Kumar J, Rao BV, Krishnaji T, Raghunadh A.