The Application of Chemometrics for Efficiency Enhancement and Toxicity Reduction in Cancer Treatment with Combined Therapy

Author:

Qian Ke1ORCID,Yan Binjun1ORCID,Xiong Yang1ORCID

Affiliation:

1. College of Pharmaceutical Sciences, Zhejiang Chinese Medical University, Hangzhou 311402, China

Abstract

Chemometrics is an important emerging discipline with unique charm formed by the intersection of mathematics, statistics, chemistry and computer science. The application of chemometrics in the field of pharmacy has injected fresh blood into the scientific research and clinical practice of medicine and has provided a sufficient scientific basis for drug analysis and content determination to solve the problem of cancer treatment with combined therapy in different ranges. This paper introduces the basic principles, advantages and disadvantages of several commonly used pattern recognition and multidimensional correction methods of chemometrics, reviews the application of chemometrics for efficiency enhancement and toxicity reduction in cancer treatment with combined therapy and summarizes its development and prospects in the future.

Funder

Basic Public Welfare Research Project of Zhejiang Province

Opening Project of Zhejiang Provincial Preponderant and Characteristic Subject of Key University (Traditional Chinese Pharmacology), Zhejiang Chinese Medical University

National Natural Science Foundation of China

Publisher

Bentham Science Publishers Ltd.

Subject

Pharmaceutical Science

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