Novel Approaches of Self Emulsifying Drug Delivery Systems and Recent Patents: A Comprehensive Review-Reference-Cited by-同舟云学术

Novel Approaches of Self Emulsifying Drug Delivery Systems and Recent Patents: A Comprehensive Review

Published:2022-04 Issue:1 Volume:9 Page:42-57
ISSN:2667-3371
Container-title:Applied Drug Research, Clinical Trials and Regulatory Affairs
language:en
Short-container-title:ADCTRA

Author:

Nandal Rimmy¹,Tahlan Sumit¹,Deep Aakash²^ORCID

Affiliation:

1. Shri Baba Mast Nath Institute of Pharmaceutical Sciences and Research, Baba Mastnath University, Rohtak 124021, India

2. Department of Pharmaceutical Sciences, Chaudhary Bansi Lal University, Bhiwani, Haryana 127021, India

Abstract

Abstract: The main aim of the current work is to set up a revolutionary Self Nano-emulsifying drug delivery system to improve the necessary bio-availability and to boost clinical efficacy when administered orally. This study's main target is to develop a novel self-nano emulsifying drug delivery system (SNEDDS) for orally administered, poorly water-soluble medicines. SNEDDS is designed to intensify weakly water dissolvable or lipophilic drugs. SNEDDS is designed to intensify weakly water dissolvable or lipophilic drugs. It contains a micro- or nano-emulsion of oil carrying medicament that spontaneously agitates an aqueous medium. For enhancing the solubility of lipophilic medicines, SNEDDS is the most significantly used in biopharmaceutics classification system [BCS class] II and IV pharmaceuticals. The improved rate of dissolution and prevention of interfacial tension are clearly demonstrated by SNEDDS. In aqueous mediums, such as gastrointestinal fluid, SNEDDS produces a stable emulsion after dilution.

Publisher

Bentham Science Publishers Ltd.

Subject

General Medicine

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