Affiliation:
1. Department of Pharmacology, Bharati Vidyapeeth (Deemed to be University), Poona College of Pharmacy,
Erandwane, Pune, 411038, Maharashtra, India
Abstract
Abstract:
Medicinal plants have significant therapeutic value and are a gift to humanity in pursuing
healthy living. The discovery of numerous rejuvenating compounds that can stop or reduce the pathology
of many diseases will be a crucial advancement in the coming years. Synthetic compounds
can cause health issues and side effects, necessitating the development of molecules derived from
plants and other natural resources as viable substitutes for synthetic compounds. Several plant phytochemicals
and extracts have been found to have significant effects on traditional medical therapy.
Murraya koenigii (M. Koenigii) is a member of the Rutaceae family, well-known in the Ayurvedic
system of medicine as a therapeutically important herb of Indian origin. M. Koenigii has been used
in several ancient systems of medicine, including Siddha and Unani, as a multi-potential medicinal
plant. Previous research has shown that this plant's bark, roots, and leaves are abundant sources of
carbazole alkaloids, which have beneficial pharmacological and biological effects. These include
antioxidant, antibacterial, antidiabetic, anti-inflammatory, antihypertensive, antifungal, antiprotozoal,
hepatoprotective, antihypercholesterolemic, antiulcer, cytotoxic, antidiarrheal, phagocytic, neuroprotective,
and antitumor activities. The key components of the M. koenigii plant and their pharmacological
activities against various diseases using preclinical models are discussed in this review.
Exhaustive studies on the molecular mechanism of action of M. koenigii are needed to validate the
effectiveness of curry tree and their constituents as potent therapeutic agents. However, serious efforts
are required to identify, isolate and evaluate the chemical components for nutritional and medicinal
potentials.
Publisher
Bentham Science Publishers Ltd.
Subject
Complementary and alternative medicine,Drug Discovery