A Dig Deep to Scout the Pharmacological and Clinical facet of Garlic (Alium Cepa)

Author:

Khan M. U.1,Khalilullah Habibullah1,Azam Faizul1,Khan Masood Alam2,Khan Arif2,Siddiqui Nasir Ali3,Mahmood Tarique4,Ahsan Farogh4,Khan Wasi Uzzaman5

Affiliation:

1. Department of Pharmaceutical Chemistry & Pharmacognosy, Unaizah College of Pharmacy, Qassim University, AlQassim, Saudi Arabia

2. Department of Basic Health Sciences, College of Applied Medical Sciences, Qassim University, Al-Qassim, Buraydah, Saudi Arabia

3. Department of Pharmacognosy, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia

4. Department of Pharmacology, Faculty of Pharmacy, Integral University, Lucknow, India

5. Department of Pharmacology & Toxicology, School of pharmaceutical education and research , India

Abstract

: Garlic, Allium sativum L. is a culinary herb that has been employed medicinally since ancient times. Garlic has been regarded as the oldest of all cultivated plants. A variety of experimental as well as human studies have been accounted that garlic is used in preventing initiation and evolution of several ailments such as hypertension, atherosclerosis, diabetes mellitus, cancer, microbial infections, arthritis, thrombosis, Alzheimer and act as anti-oxidant. The preclinical toxicity study gives an impression that garlic is safe, although allergic reactions may occur. Recently there has been systematic research regarding garlic, and positive results have been attained in healing many diseases, for centuries many countries of different civilization and continents have protecting their populations and healing themselves by using garlic. Therefore, there is an augmented necessity of investigation on the history of garlic for the sake of strengthening the ability of physicians and pharmacist to reply to the challenges arising in the provision of specialized facilities to serve mankind. The present review provides morphological, pharmacological and toxicological insight regarding garlic. Advancement in studies are required to explicate the therapeutic mode of action of the garlic along with its potency, effectiveness and clinical wellbeing in management of different ailments.

Publisher

Bentham Science Publishers Ltd.

Subject

Complementary and alternative medicine,Drug Discovery

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