Affiliation:
1. Department of Pharmaceutical Chemistry, Dr. D.Y. Patil Institute of Pharmaceutical Sciences & Research, Pimpri,
Pune-411018, Maharashtra, India
Abstract
Background:
Various varieties of rice (Oryza sativa) have been exploited for a variety of
purposes since ancient times, with the integration into foods, cosmetics, and pharmaceutical products.
A huge diversity is seen in the cultivated rice variety based on regions, area, and climatic conditions
responsible for variation in chemical composition leading to enriched supplements beneficial
for health conditions. Among the varieties available, red rice extract is now increasingly recognized
for its antioxidant, anti-inflammatory activity, anti-diabetic, anti-hyperlipidemic activity, and bone
formation.
Objective:
There is a need to validate the nutritional and supplement values through appropriate analytical
and pharmacological studies and create awareness for the end users regarding the value of
red rice.
Results:
In the present article attempt is done to reviewthe variety of red rice based on geographical
origin, and the impact on nutritional and medicinal value. Further elaborating the extraction techniques
which can help optimize the extraction efficiency of polyphenols known for their antioxidant
properties. Polyphenolic phytoconstituents belonging to phenolic acids, and flavonoids include, flavonols,
flavones, flavanols, flavanones, and isoflavones, to name a few. Anthocyanins, and proanthocyanidins
make the pigment part of the outer layer and bran of the rice and contain the monomers
of catechin, epicatechin, gallocatechin, and epigallocatechin units. The quantification of the
phytoconstituents using chromatographical methods can help in evaluation of the red rice for its
quality and design formulation with desired efficacy.
Conclusion:
With the vast varieties of red rice available, quantification of important bio-actives
can help in maintaining quality of final product. Various targeted pharmacological actions reported
include anti-inflammatory, antihyperlipidemic, antidiabetic, anticancer and antioxidant produced by
the rice, mainly by virtue of the polyphenolic content, contribute in achieving a value to rice as
nourishment and a safe therapeutic product which can be consumed as a nutraceutical or pharmaceutical
ingredient.
Publisher
Bentham Science Publishers Ltd.
Subject
Complementary and alternative medicine,Drug Discovery