Nature-derived Quinolines and Isoquinolines: A Medicinal Chemistry Perspective-Reference-Cited by-同舟云学术

Nature-derived Quinolines and Isoquinolines: A Medicinal Chemistry Perspective

Published:2021-02-04 Issue:1 Volume:7 Page:72-92
ISSN:2215-0838
Container-title:Current Traditional Medicine
language:en
Short-container-title:CTM

Author:

Gupta Mohit¹,Patel Saloni¹

Affiliation:

1. Division of Medicinal Chemistry, Graduate School of Pharmaceutical Sciences, Duquesne University, 600 Forbes Avenue, Pittsburgh, Pennsylvania 15282, United States

Abstract

Quinoline and isoquinoline motifs are commonly encountered in natural products of diverse origins. These moderately basic fused-heterocyclic rings containing natural products are adorned with remarkable biological activities with clinical use in various diseases demonstrating nature elegance and creativity. Therefore, these privileged rings have attracted profound interest from the scientific community. In this perspective, we have discussed medicinal chemistry perspective of the natural products containing quinoline and isoquinoline scaffolds.

Publisher

Bentham Science Publishers Ltd.

Subject

Complementary and alternative medicine,Drug Discovery

Reference113 articles.

1. Joule J.; Mills K.; Smith G.; Quinolines and isoquinolines: Reactions and synthesis Heterocyclic Chemistry 1995,120-145

2. Michael J.P.; Quinoline, quinazoline and acridone alkaloids. Nat Prod Rep 1997,14(1),11-20

3. Menachery M.D.; Lavanier G.L.; Wetherly M.L.; Guinaudeau H.; Shamma M.; Simple isoquinoline alkaloids. J Nat Prod 1986,49(5),745-778

4. Mann J.; Davidson R.S.; Hobbs J.B.; Banthorpe D.V.; Harborne J.B.; Natural products: Their chemistry and biological significance 1994,455

5. Hawkins K.M.; Smolke C.D.; Production of benzylisoquinoline alkaloids in Saccharomyces cerevisiae. Nat Chem Biol 2008,4(9),564-573

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