Recent Patents on Plant-Derived Nanoparticles and their Potential Application Towards Various Cancer Therapeutics

Abstract

Background: Nanotechnology plays a vital role in the field of medicine. Especially various nanoparticles such as silver, gold, platinum are involved in the treatment of different types of cancer. The effective nanoparticles were synthesized using techniques like chemical, physical, electrochemical and biological methods. In order to overcome the limitations existing in the synthesis of nanoparticles, researchers turned their attention toward the biological single step nanoparticle synthesis method by using plant and plant products. Objective: The objective of this study is to overcome the side effects encountered in the existing anti-cancer agents like nonspecificity and fast excretion, and plant-derived nanoparticles that are eco-friendly, cost-effective and biologically active could serve as a promising alternative. Conclusion: From the thorough literature review and recent patents, it is understood that the plant-derived nanoparticles exhibited an excellent anti-proliferation anti-tumor activity towards different types of cancers without affecting the normal cells. Especially, the traditional chemotherapeutic drugs obtained from the plant source incorporated with the nanoparticles show remarkable results against anti cancer studies. The present review focused on some of the existing herbal plant derived nanoparticles, formulations and their potential application in cancer therapeutics.