Affiliation:
1. Department of Cardiology, Hayat Hospital, Malatya, Turkey
Abstract
Vascular diseases are the main reason for morbidity and mortality worldwide. As we know,
the earlier phase of vascular diseases is endothelial dysfunction in humans, the endothelial tissues play
an important role in inflammation, coagulation, and angiogenesis, via organizing ligand-receptor associations
and the various mediators’ secretion. We can use many inflammatory non-invasive tests (flowmediated
dilatation, epicedial fat thickness, carotid-intima media thickness, arterial stiffness and anklebrachial
index) for assessing the endothelial function. In addition, many biomarkers (ischemia modified
albumin, pentraxin-3, E-selectin, angiopoietin, endothelial cell specific molecule 1, asymmetrical dimethylarginine,
von Willebrand factor, endothelial microparticles and endothelial progenitor cells) can
be used to evaluate endothelial dysfunction. We have focused on the relationship between endothelial
dysfunction and inflammatory markers of vascular disease in this review.
Publisher
Bentham Science Publishers Ltd.
Subject
Cardiology and Cardiovascular Medicine,Pharmacology
Reference60 articles.
1. Theodorou K.; Boon R.A.; Endothelial Cell Metabolism in Atherosclerosis. Front Cell Dev Biol 2018,6,82
2. Tabas I.; García-Cardeña G.; Owens G.K.; Recent insights into the cellular biology of atherosclerosis. J Cell Biol 2015,209(1),13-22
3. Tousoulis D.; Charakida M.; Stefanadis C.; Endothelial function and inflammation in coronary artery disease. Heart 2006,92(4),441-444
4. Balta S.; Mikhailidis D.P.; Demirkol S.; Ozturk C.; Celik T.; Iyisoy A.; Endocan: A novel inflammatory indicator in cardiovascular disease? Atherosclerosis 2015,243(1),339-343
5. Libby P.; The molecular mechanisms of the thrombotic complications of atherosclerosis. J Intern Med 2008,263(5),517-527
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