Unlocking the Role of Virus-like Particles (VLPs) for Cancer Treatment

Author:

S Venishaa1,Kumar Prashant2,Sen Aniruddha3,Anand Amit4,Kaushik Monika5,Bhowmick Mithun6ORCID,Bhowmick Pratibha7ORCID,Ashique Sumel7ORCID

Affiliation:

1. Department of Nanoscience and Technology, Bharathiar University, 641046, Coimbatore, India

2. Teerthanker Mahaveer College of Pharmacy, Teerthanker Mahaveer University Moradabad Uttar Pradesh, 244001, India

3. Department of Biochemistry, All India Institute of Medical Sciences, Gorakhpur, Uttar Pradesh, 273008, India

4. Department of Pharmacognosy, JSS College of Pharmacy, Mysuru, JSS Academy of Higher Education and Research, Mysuru, Karnataka, 570015 India

5. Department of Pharmacology, Amity Institute of Pharmacy, Amity University Gwalior, 474005, Madhya Pradesh, India

6. Department of Pharmaceutical Sciences, Bengal College of Pharmaceutical Sciences and Research, Durgapur, 713212, West Bengal, India

7. Department of Pharmaceutical Sciences, Bengal College of Pharmaceutical Sciences and Research, Durgapur, 713212, West Bengal, India

Abstract

Abstract: Self-assembling structures that look similar to viruses in broad terms but do not contain viral genetic material are known as virus-like particles. These particles, made up of viral structural proteins, can have size, shape, and surface characteristics similar to natural viruses. The breakthrough potential of virus-like particles, or VLPs, as a novel cancer therapy strategy is explored in this article. Starting with describing the problems facing cancer therapy today, the emphasis moves to an in-depth study of VLPs, including their different sizes, shapes, and structural characteristics. With insights into drug encapsulation techniques and their implications for anticancer therapy, integrating VLPs into drug delivery systems is important. The article highlights the multiple roles vector lambda polymorphs (VLPs) play in improving diagnostic methods by exploring their dual functioning in medication delivery and imaging. To address concerns about safety and biocompatibility, the paper critically analyses the toxicity study of VLPs. It provides a comprehensive review, touching on ongoing clinical trials and significant patents that impact the environment.

Publisher

Bentham Science Publishers Ltd.

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