Loneliness as Risk Factor for Alzheimer´s disease

Author:

Ávila Jesús12ORCID,Fernández-Blázquez Miguel A.3,Ávila-Villanueva Marina4,Gómez-Ramírez Jaime5ORCID

Affiliation:

1. Center of Molecular Biology Severo Ochoa (CSIC-UAM), Campus de Cantoblanco, Madrid, Spain

2. Network Center for Biomedical Research in Neurodegenerative Diseases (CIBERNED), Madrid, Spain

3. Department of Biological Psychology and Health, Autonomous University of Madrid, Campus de Cantoblanco, Madrid, Spain

4. Department of Experimental Psychology, Cognitive Processes and Speech Therapy, Complutense University of Madrid (UCM), Campus de Somosaguas, Pozuelo de Alarcón, Madrid, Spain

5. Neuropsychology Department, Universidad de Cádiz, Cádiz, Spain

Abstract

Abstract: There is considerable empirical evidence that unequivocally points to loneliness as a modifiable risk factor for the development of Alzheimer's disease and other related dementias. With the emergence of the COVID-19 pandemic and the resulting lockdown and social distancing, there has been a renewed interest in studying this topic. The present review examines the links between loneliness and Alzheimer's disease, with particular emphasis on the mechanisms common to both conditions.

Funder

Ministerio de Ciencia e Innovación

Publisher

Bentham Science Publishers Ltd.

Subject

General Medicine

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