Affiliation:
1. Chitkara College of Pharmacy, Chitkara University, Punjab, India
2. Department of Chemistry and Pharmacy, University of Sassari 07100, Italy
Abstract
Natural products form a significant portion of medicinal agents that are currently used for
the management of cancer. All these natural products have unique structures along with diverse action
mechanisms with the capacity to interact with different therapeutic targets of several complex disorders.
Although plants contribute as a major source of natural products with anti-cancer potential, the
marine environment and microbes have also bestowed some substantial chemotherapeutic agents. A
few examples of anti-cancer agents of natural origin include vincristine, vinblastine, paclitaxel, camptothecin
and topotecan obtained from plants, bryostatins, sarcodictyin and cytarabine from marine organisms
and bleomycin and doxorubicin from micro-organisms (dactinomycin, bleomycin and doxorubicin).
The incredible diversity in the chemical structures and biological properties of compounds
obtained from million species of plants, marine organisms and microorganisms present in nature has
commenced a new era of potential therapeutic anti-cancer agents.
Publisher
Bentham Science Publishers Ltd.
Subject
Drug Discovery,Pharmacology,General Medicine
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