Affiliation:
1. Centre of Bioanalysis, National Institute of Biological Sciences, Bucharest, Romania
2. Faculty of Applied Chemistry and Materials Science, University Politehnica Bucharest, Romania
Abstract
Since early times, various plants have been used as remedies for treating different kinds of
diseases and lesions with satisfying results. The phenolic compounds are secondary metabolites from
medicinal plants which include a wide category of compounds such as phenolic acids, flavonoids, tannins,
stilbenes, curcuminoids, xanthones, coumarins, lignans, etc. Between these, lignans are considered
important in cancer prevention and treatment, besides other beneficial health effects, e.g. antioxidant,
anticarcinogenic, antimutagenic, and anti-estrogenic effects. This review summarizes the most
recent literature and the most important results concerning plant lignans and their derivatives in cancer
prevention and treatment, both in vitro and in vivo assessments. The mechanistic aspects will be also
highlighted.
Publisher
Bentham Science Publishers Ltd.
Subject
Drug Discovery,Pharmacology,General Medicine
Cited by
21 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献