Affiliation:
1. Department of Chemistry, School of Sciences, Gujarat University, Ahmedabad, Gujarat, India
2. Piramal Enterprise Ltd, Plot No.-18, Pharmez, Matoda Village, Ahmedabad, India
Abstract
In the last 2-3 decades, the broad research in the application of benzimidazole derivatives
made it important for mankind. Many scientists have worked on benzimidazole derivatives and they
found that this compound has a diverse role in the field of medicinal chemistry. Few benzimidazole derivatives
are currently in the market as a drug candidate against various diseases. Moreover, the benzimidazole
derivatives exhibit pharmacological activities such as anti-tuberculosis, anti-malarial, antihistamine,
antimicrobial, antiviral, antidiabetic, anticancer, anti-fungal, anti-inflammatory, analgesic,
anti-HIV, etc. In this review, we have summarized various derivatives of benzimidazole which have
been prepared by many researchers to understand the chemistry as well as diverse pharmacological activities.
These findings may lead the scientists who are working in the field of medicinal chemistry to
the development of benzimidazole based drug candidates in the future.
Funder
Rajiv Gandhi National Fellowship
Publisher
Bentham Science Publishers Ltd.
Subject
Drug Discovery,Pharmacology,General Medicine
Cited by
66 articles.
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