Affiliation:
1. Chitkara College of Pharmacy, Chitkara University, Punjab, India
Abstract
The compound 4-hydroxy-3-methoxycinnamic acid, named as ferulic acid (FA), is a ubiquitous phenolic
compound which is distributed extensively in the plant kingdom. Ferulic acid is a boon as it shows immense potential
therapeutic effects which are useful in the treatment of diabetes, cancer, pulmonary and CVS diseases majorly due to its
anti-oxidant and anti-inflammatory action. Ferulic acid exhibits other wide variety of biological activities such as,
anticarcinogenic, antiallergic, antimicrobial, antiviral, hepatoprotective, metal chelation, activation of transcriptional
factors, modulation of enzyme activity, gene expression as well as signal transduction. The structural characteristics of this
active ingredient make it an optimal substrate to form or synthesize various derivates and its formulations. The present
review addresses structure of ferulic acid, its pharmacodynamic parameters, applications and its various derivatives. In
addition, the review also aims to cover the main aspects related to use of ferulic acid in the food and health industry and
have listed various published patents on Ferulic acid.
Publisher
Bentham Science Publishers Ltd.
Subject
Drug Discovery,Pharmacology,General Medicine
Cited by
15 articles.
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