Diverse Thiophenes as Scaffolds in Anti-cancer Drug Development: A Concise Review-Reference-Cited by-同舟云学术

Diverse Thiophenes as Scaffolds in Anti-cancer Drug Development: A Concise Review

Published:2021-02-09 Issue:2 Volume:21 Page:217-232
ISSN:1389-5575
Container-title:Mini-Reviews in Medicinal Chemistry
language:en
Short-container-title:MRMC

Author:

Bhilare Neha V.¹^ORCID,Auti Pratibha B.²,Marulkar Vinayak S.¹,Pise Vilas J.¹

Affiliation:

1. Department of Pharmaceutical Chemistry, Arvind Gavali College of Pharmacy, Satara-415004, Maharashtra, India

2. Department of Pharmaceutical Chemistry, Sinhagad Institute of Pharmacy, Narhe, Pune-411041, Maharashtra, India

Abstract

Thiophenes are one of the abundantly found heterocyclic ring systems in many biologically active compounds. Moreover, various substituted thiophenes exert numerous pharmacological actions on account of their isosteric resemblance with compounds of natural origin, thus rendering them with diverse actions like antibacterial, antifungal, antiviral, anti-inflammatory, analgesic, antiallergic, hypotensives, etc. In this review, we specifically explore the chemotherapeutic potential of a variety of structures consisting of thiophene scaffolds as prospective anticancer agents.

Publisher

Bentham Science Publishers Ltd.

Subject

Drug Discovery,Pharmacology,General Medicine

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