A Review on Recent Synthetic Strategies and Pharmacological Importance of 1,3-Thiazole Derivatives
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Published:2019-01-11
Issue:3
Volume:19
Page:215-238
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ISSN:1389-5575
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Container-title:Mini-Reviews in Medicinal Chemistry
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language:en
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Short-container-title:MRMC
Author:
Nayak Swarnagowri1, Gaonkar Santhosh L.1
Affiliation:
1. Department of Chemistry, Manipal Institute of Technology, Manipal Academy of Higher Education, Manipal, 576104, Karnataka, India
Abstract
Thiazole is the most common heterocyclic compound in heterocyclic chemistry and in drug
design. Presence of several reaction sites in the thiazole moiety extends their range of applications and
leads to new solutions for challenges in synthetic and medicinal chemistry. Thiazole derivatives are
widely used as bioactive agents, liquid crystals, sensors, catalysts, etc. The motivating molecular architecture
of 1,3-thiazoles makes them suitable moieties for drug development. In this review, our aim is
to corroborate the recent data available on various synthetic strategies and biological properties of 1,3-
thiazole derivatives.
Publisher
Bentham Science Publishers Ltd.
Subject
Drug Discovery,Pharmacology,General Medicine
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