Hypericum spp.: An Update on the Biological Activities and Metabolic Profiles

Author:

Marrelli Mariangela1ORCID,Statti Giancarlo1ORCID,Conforti Filomena1ORCID

Affiliation:

1. Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, I-87036 Rende, (CS), Italy

Abstract

: Plants from the genus Hypericum, one genus of the Hypericaceae family, have attracted a lot of attention for their potential pharmaceutical applications. Most of the studies in the literature focus on H. perforatum L. (common St. John's wort), whose complex spectrum of bioactive compounds makes this species one of the top herbal remedies and supplements in the world. It is also important to compare the studies on other Hypericum species, both from the phytochemical and biological point of view. The aim of this review was to provide an update of most recent studies about biological investigations of plants belonging to Hypericum genus. The metabolic profiles of Hypericum spp. were also discussed in order to present a spectrum of secondary metabolites not previously identified in this genus.

Publisher

Bentham Science Publishers Ltd.

Subject

Drug Discovery,Pharmacology,General Medicine

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